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DODMA is a cationic lipid used in the preparation of lipid nanoparticles for drug delivery. Its pH-titratable head group remains neutral at physiological pH for systemic circulation, but protonates in the acidic environment of endosomes, facilitating fusion with the endosome membrane and aiding nucleic acid release.
Cationic lipid
Can be used to prepare lipid nanoparticles
Can be used for drug delivery
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